Tissue injuries after single-port and multiport laparoscopic gynecologic surgeries

A prospective multicenter study

Kyeong A. So, Jae Kwan Lee, Jae Yun Song, Jae Won Kim, Nak Woo Lee, Kyung Do Ki, Jong Min Lee, Yong Jung Song, Yong Jin Na, Chun Hoe Ku, Jin Woo Shin, Chul Jung Kim, Un Suk Jung

Research output: Contribution to journalArticle

Abstract

The present study focused on the degree of tissue injury following single-port laparoscopic surgery (SPLS) and multiport laparoscopic surgery (MPLS) for the treatment of various benign gynecologic diseases. A total of 228 patients were prospectively enrolled at seven academic centers in South Korea between April 2011 and September 2012. Of these, 122 patients underwent SPLS and 106 patients underwent MPLS. The serum levels of C-reactive protein, creatine phosphokinase, lactic dehydrogenase and cancer antigen 125 were measured preoperatively and on postoperative day 4 by immunonephelometry. Cosmetic satisfaction and postoperative pain scores (visual analogue scale) were analyzed. Postoperative changes in the levels of the serum markers were found to be similar between the SPLS and MPLS groups. However, the postoperative pain scores at 48 h were significantly lower in the SPLS group when compared with those in the MPLS (P=0.001). In addition, patient-controlled analgesia was used more frequently by patients in the MPLS group (P=0.003). The present study is the first prospective investigation of tissue injury resulting from SPLS and MPLS in gynecology. In conclusion, the current study demonstrated that serum marker levels during SPLS were similar to those during MPLS in the treatment of benign gynecologic diseases. However, SPLS is a reasonable alternative to MPLS and is associated with comparable tissue injury, improved cosmesis and reduced postoperative pain.

Original languageEnglish
Pages (from-to)2230-2236
Number of pages7
JournalExperimental and Therapeutic Medicine
Volume12
Issue number4
DOIs
Publication statusPublished - 2016 Oct 1

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Gynecologic Surgical Procedures
Laparoscopy
Multicenter Studies
Prospective Studies
Wounds and Injuries
Postoperative Pain
Female Genital Diseases
Biomarkers
Patient-Controlled Analgesia
Republic of Korea
Creatine Kinase
Gynecology
Visual Analog Scale
Cosmetics
C-Reactive Protein
Protein Kinases

Keywords

  • Benign gynecologic disease
  • Single-port laparoscopy
  • Tissue injuries

ASJC Scopus subject areas

  • Immunology and Microbiology (miscellaneous)
  • Cancer Research

Cite this

Tissue injuries after single-port and multiport laparoscopic gynecologic surgeries : A prospective multicenter study. / So, Kyeong A.; Lee, Jae Kwan; Song, Jae Yun; Kim, Jae Won; Lee, Nak Woo; Ki, Kyung Do; Lee, Jong Min; Song, Yong Jung; Na, Yong Jin; Ku, Chun Hoe; Shin, Jin Woo; Kim, Chul Jung; Jung, Un Suk.

In: Experimental and Therapeutic Medicine, Vol. 12, No. 4, 01.10.2016, p. 2230-2236.

Research output: Contribution to journalArticle

So, Kyeong A. ; Lee, Jae Kwan ; Song, Jae Yun ; Kim, Jae Won ; Lee, Nak Woo ; Ki, Kyung Do ; Lee, Jong Min ; Song, Yong Jung ; Na, Yong Jin ; Ku, Chun Hoe ; Shin, Jin Woo ; Kim, Chul Jung ; Jung, Un Suk. / Tissue injuries after single-port and multiport laparoscopic gynecologic surgeries : A prospective multicenter study. In: Experimental and Therapeutic Medicine. 2016 ; Vol. 12, No. 4. pp. 2230-2236.
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