Transcriptome analysis reveals the ahr, smad2/3, and hif-1α pathways as the mechanism of ochratoxin a toxicity in kidney cells

Medicine & Life Sciences

• Ochratoxins 100%
• ochratoxin A 65%
• Gene Expression Profiling 61%
• Kidney 31%
• Epithelial-Mesenchymal Transition 23%
• Caspase 3 19%
• Small Interfering RNA 18%
• RNA-Seq 17%
• Wounds and Injuries 14%
• Apoptosis 13%
• Transcription Factor 3 10%
• Down-Regulation 10%
• Mycotoxins 9%
• RNA Sequence Analysis 8%
• Xenobiotics 8%
• Cadherins 7%
• Fibronectins 7%
• Real-Time Polymerase Chain Reaction 5%
• Hypoxia 5%
• Epithelial Cells 5%
• Food 5%
• Genes 2%

Chemical Compounds

• Ochratoxin A 76%
• Silencing RNA 46%
• Marker 20%
• RNA Sequencing 19%
• Fibronectin 14%
• Mycotoxin 13%
• Xenobiotic Agent 13%
• Pharmacological Metabolism 9%
• Food 8%