cis-AB, a rare ABO genotype, is the result of a mutated gene resulting in dual specific hybrid enzymes. A single-point mutation reverses the specificity of human blood group B synthesizing galactosyltransferase. This may lead to misclassification in ABO grouping and adverse transfusion reactions. Recently, the authors experienced a case of a patient with cis-AB blood type undergoing pulmonary valve replacement and tricuspid valvuloplasty. We transfused the patient with Rh+ A packed red blood cell, fresh frozen plasma and platelet concentrates without any clinically significant transfusion reaction.
|Number of pages||2|
|Journal||British Journal of Anaesthesia|
|Publication status||Published - 2005 Jun|
- Blood, transfusion
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine