Treatment of ranula in pediatric patients with intralesional injection of OK-432

Heung Man Lee, Hyun Woo Lim, Hee Joon Kang, Sung Won Chae, Soon Jae Hwang, Kwang Yoon Jung, Jeong Soo Woo

Research output: Contribution to journalReview article

15 Citations (Scopus)

Abstract

OBJECTIVE: To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432. STUDY DESIGN:: Retrospective analysis of 13 cases. METHODS: Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005. RESULTS: Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed. CONCLUSIONS: On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.

Original languageEnglish
Pages (from-to)966-969
Number of pages4
JournalLaryngoscope
Volume116
Issue number6
DOIs
Publication statusPublished - 2006 Jun

Keywords

  • Children
  • OK-432
  • Ranula

ASJC Scopus subject areas

  • Otorhinolaryngology

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    Lee, H. M., Lim, H. W., Kang, H. J., Chae, S. W., Hwang, S. J., Jung, K. Y., & Woo, J. S. (2006). Treatment of ranula in pediatric patients with intralesional injection of OK-432. Laryngoscope, 116(6), 966-969. https://doi.org/10.1097/01.Mlg.0000216809.90196.83