Trends and outcomes of transcatheter aortic valve implantation (TAVI) in Korea: The results of the first cohort of Korean TAVI registry

Cheol Woong Yu, Won Jang Kim, Jung Min Ahn, Hyungdon Kook, Se Hun Kang, Jung Kyu Han, Young Guk Ko, Seung Hyuk Choi, Bon Kwon Koo, Kiyuk Chang, Hyo Soo Kim

    Research output: Contribution to journalArticlepeer-review

    10 Citations (Scopus)

    Abstract

    Background and Objectives: There has been no nation-wide data on the outcomes of transcatheter aortic valve implantation (TAVI) afer commercialization of TAVI in Korea. We report clinical features and outcomes of the frst cohort of TAVI performed from Jun 2015 to Jun 2017 in Korea. Methods: The frst cohort of Korean-TAVI (K-TAVI) registry includes 576 consecutive patients with severe symptomatic aortic stenosis who underwent TAVI from 17 Korean hospitals for 2 years. Results: Most of TAVI procedures were performed for septuagenarians and octogenarians (90.8%) through transfemoral approach (98.3%). The rate of device success was 92.5% and permanent pacemaker was implanted in 5.6%. In successive years, incidences of paravalvular leakage (PVL) and major bleeding declined. Society of Thoracic Surgeons (STS) score was 5.2 (3.0 to 9.0) and 34.7% of patients had high surgical risk (STS =8). One-year all-cause death occurred in 8.9% and was signifcantly lower in low to intermediate risk one than in high risk (5.4% vs. 15.5%, p<0.001). The independent predictors of 1-year mortality were age (hazard ratio [HR], 1.087; 95% confdence interval [CI], 1.036-1.141; p=0.001), moderate or severe PVL (HR, 4.631; 95% CI, 1.624-13.203; p=0.004) and end-stage renal disease (HR, 5.785; 95% CI, 2.717-12.316; p<0.001). Conclusions: K-TAVI registry showed favorable 1-year outcomes with decreasing complication rate over time in real-world Korean patients. Two-thirds of patients were low to intermediate surgical risk and showed a signifcantly lower mortality than the high-risk patients, suggesting the promising future on the expanded indications of TAVI.

    Original languageEnglish
    Pages (from-to)382-394
    Number of pages13
    JournalKorean Circulation Journal
    Volume48
    Issue number5
    DOIs
    Publication statusPublished - 2018 May

    Keywords

    • Aortic valve stenosis
    • Koreans
    • Mortality
    • Transcatheter aortic valve replacement

    ASJC Scopus subject areas

    • Internal Medicine
    • Cardiology and Cardiovascular Medicine

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