Tunable sheathless microfluidic focusing using ion concentration polarization

Junghyo Yoon, Youngkyu Cho, Jeong Hoon Lee, Seok Chung

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2 Citations (Scopus)

Abstract

In this study, we developed a tunable sheathless focusing method for focusing micrometer- and nanometer-sized particles, using ion concentration polarization (ICP) in an ion-selective, resin-coated channel. The particle movement was regulated using an electric field, and by varying the flow rate and ionic strength of the liquid solution; various phenomena were observed, depending on the particle properties. Here, we provide insights into the physical basis of the ICP-focusing phenomena, and a statistical approach for analyzing the particle movement. This ICP-focusing technology is an approach that could be applied for the separation and sorting of various particles, including cells, proteins, and bacteria.

Original languageEnglish
Article number083507
JournalApplied Physics Letters
Volume107
Issue number8
DOIs
Publication statusPublished - 2015 Aug 24

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ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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