TY - JOUR
T1 - Tunable sheathless microfluidic focusing using ion concentration polarization
AU - Yoon, Junghyo
AU - Cho, Youngkyu
AU - Lee, Jeong Hoon
AU - Chung, Seok
PY - 2015/8/24
Y1 - 2015/8/24
N2 - In this study, we developed a tunable sheathless focusing method for focusing micrometer- and nanometer-sized particles, using ion concentration polarization (ICP) in an ion-selective, resin-coated channel. The particle movement was regulated using an electric field, and by varying the flow rate and ionic strength of the liquid solution; various phenomena were observed, depending on the particle properties. Here, we provide insights into the physical basis of the ICP-focusing phenomena, and a statistical approach for analyzing the particle movement. This ICP-focusing technology is an approach that could be applied for the separation and sorting of various particles, including cells, proteins, and bacteria.
AB - In this study, we developed a tunable sheathless focusing method for focusing micrometer- and nanometer-sized particles, using ion concentration polarization (ICP) in an ion-selective, resin-coated channel. The particle movement was regulated using an electric field, and by varying the flow rate and ionic strength of the liquid solution; various phenomena were observed, depending on the particle properties. Here, we provide insights into the physical basis of the ICP-focusing phenomena, and a statistical approach for analyzing the particle movement. This ICP-focusing technology is an approach that could be applied for the separation and sorting of various particles, including cells, proteins, and bacteria.
UR - http://www.scopus.com/inward/record.url?scp=84940538585&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84940538585&partnerID=8YFLogxK
U2 - 10.1063/1.4929816
DO - 10.1063/1.4929816
M3 - Article
AN - SCOPUS:84940538585
SN - 0003-6951
VL - 107
JO - Applied Physics Letters
JF - Applied Physics Letters
IS - 8
M1 - 083507
ER -