Abstract
Herein, we report a facile one-step synthetic strategy for fabrication of three (blue, green and yellow) fluorescent color carbon dots (CDs) from tomato (Solanum lycopersicum). The as-synthesized CDs showed emission peaks at 450, 520 and 560 nm for blue, green and yellow color CDs when excited at 370, 420 and 460 nm, respectively. Using tomato as a carbon source, the fabricated three fluorescent color CDs showed good water dispersity and high quantum yield. The analytical performances of three fluorescent color CDs are evaluated by detecting Fe 3+ ion in biofluids and iron tablets. Upon the addition of Fe 3+ ion under optimal conditions, the fluorescence intensity of three fluorescent color CDs was quenched linearly over the range of 0.1 to 2.0 μM. This method opens a new analytical strategy to quantify Fe 3+ ion in iron tablets and biofluids with high sensitivity. Further, the uptake of three fluorescent color CDs into HeLa cells was confirmed by confocal laser scanning microscopy. Intracellular experiments demonstrated that the three fluorescent color CDs were effectively internalized the cells and show excellent biocompatibility and low toxicity, suggesting that the CDs can be used as good candidates for biomedical applications.
| Original language | English |
|---|---|
| Pages (from-to) | 834-842 |
| Number of pages | 9 |
| Journal | Materials Science and Engineering C |
| Volume | 98 |
| DOIs | |
| Publication status | Published - 2019 May 1 |
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Keywords
- Cancer cells
- Fe ion
- Fluoresce spectroscopy and microscopy
- Fluorescent carbon dots
- Tomato
ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics
- Mechanics of Materials
- Mechanical Engineering
Cite this
Tuning of carbon dots emission color for sensing of Fe 3+ ion and bioimaging applications . / Kailasa, Suresh Kumar; Ha, Siyoung; Baek, Seung Hoon; Phan, Le Minh Tu; Kim, Sangjun; Kwak, Kyungwon; Park, Tae Jung.
In: Materials Science and Engineering C, Vol. 98, 01.05.2019, p. 834-842.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Tuning of carbon dots emission color for sensing of Fe 3+ ion and bioimaging applications
AU - Kailasa, Suresh Kumar
AU - Ha, Siyoung
AU - Baek, Seung Hoon
AU - Phan, Le Minh Tu
AU - Kim, Sangjun
AU - Kwak, Kyungwon
AU - Park, Tae Jung
PY - 2019/5/1
Y1 - 2019/5/1
N2 - Herein, we report a facile one-step synthetic strategy for fabrication of three (blue, green and yellow) fluorescent color carbon dots (CDs) from tomato (Solanum lycopersicum). The as-synthesized CDs showed emission peaks at 450, 520 and 560 nm for blue, green and yellow color CDs when excited at 370, 420 and 460 nm, respectively. Using tomato as a carbon source, the fabricated three fluorescent color CDs showed good water dispersity and high quantum yield. The analytical performances of three fluorescent color CDs are evaluated by detecting Fe 3+ ion in biofluids and iron tablets. Upon the addition of Fe 3+ ion under optimal conditions, the fluorescence intensity of three fluorescent color CDs was quenched linearly over the range of 0.1 to 2.0 μM. This method opens a new analytical strategy to quantify Fe 3+ ion in iron tablets and biofluids with high sensitivity. Further, the uptake of three fluorescent color CDs into HeLa cells was confirmed by confocal laser scanning microscopy. Intracellular experiments demonstrated that the three fluorescent color CDs were effectively internalized the cells and show excellent biocompatibility and low toxicity, suggesting that the CDs can be used as good candidates for biomedical applications.
AB - Herein, we report a facile one-step synthetic strategy for fabrication of three (blue, green and yellow) fluorescent color carbon dots (CDs) from tomato (Solanum lycopersicum). The as-synthesized CDs showed emission peaks at 450, 520 and 560 nm for blue, green and yellow color CDs when excited at 370, 420 and 460 nm, respectively. Using tomato as a carbon source, the fabricated three fluorescent color CDs showed good water dispersity and high quantum yield. The analytical performances of three fluorescent color CDs are evaluated by detecting Fe 3+ ion in biofluids and iron tablets. Upon the addition of Fe 3+ ion under optimal conditions, the fluorescence intensity of three fluorescent color CDs was quenched linearly over the range of 0.1 to 2.0 μM. This method opens a new analytical strategy to quantify Fe 3+ ion in iron tablets and biofluids with high sensitivity. Further, the uptake of three fluorescent color CDs into HeLa cells was confirmed by confocal laser scanning microscopy. Intracellular experiments demonstrated that the three fluorescent color CDs were effectively internalized the cells and show excellent biocompatibility and low toxicity, suggesting that the CDs can be used as good candidates for biomedical applications.
KW - Cancer cells
KW - Fe ion
KW - Fluoresce spectroscopy and microscopy
KW - Fluorescent carbon dots
KW - Tomato
UR - http://www.scopus.com/inward/record.url?scp=85059931262&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85059931262&partnerID=8YFLogxK
U2 - 10.1016/j.msec.2019.01.002
DO - 10.1016/j.msec.2019.01.002
M3 - Article
C2 - 30813090
AN - SCOPUS:85059931262
VL - 98
SP - 834
EP - 842
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
SN - 0928-4931
ER -