Two cases of cutaneous squamous cell carcinoma with intracranial extension

Ji Min Lee, Jung Jin Shin, Hee Won Jang, Min Gun Yoo, Soo Hong Seo, Il Hwan Kim

    Research output: Contribution to journalArticlepeer-review


    Cutaneous squamous cell carcinoma (SCC) is the second most common skin malignant neoplasm. Cutaneous SCC shows a broad spectrum, ranging from easily managed superficial tumors to highly infiltrative, metastasizing ones that can cause death. We have experienced two patients with SCC with intracranial extension. One case was an 88-year-old man with a tumor on the forehead treated with Mohs micrographic surgery who presented with local recurrence at the perilesional region of the primary site after 3 years. Wide excision was performed, and histologic findings showed a SCC that extended to the dura mater. The other case was a 69-year-old woman who presented with an erythematous 2×4 cm-sized plaque on the right temple, and a biopsy examination revealed SCC. The patient refused surgery and 7 months later, presented with a 5×10 cm-sized oozing plaque with multiple ulcers. Radiologic evaluation demonstrated intracranial invasion and right retropharyngeal metastatic lymph nodes. She was treated with radiotherapy for 4 months.

    Original languageEnglish
    Pages (from-to)56-61
    Number of pages6
    JournalKorean Journal of Dermatology
    Issue number1
    Publication statusPublished - 2016 Jan


    • Cutaneous squamous cell carcinoma
    • Intracranial extension
    • Local recurrence
    • Metastasis
    • Mohs micrographic surgery

    ASJC Scopus subject areas

    • Dermatology


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