Two cases of primary malignant melanoma of the lacrimal sac

Heung Man Lee, Hee Joon Kang, Geon Choi, Sungwon Chae, Chul Hwan Kim, Soon Jae Hwang, Sang Hag Lee

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background. Malignancy of the lacrimal sac is rare, and primary malignant melanoma in this region is extremely rare. Methods. We report two cases of malignant melanoma of the lacrimal sac presented with epiphora and a palpable mass in the medial canthal area. We performed radical surgery and radiation therapy. Results. The light microscopic, immunohistochemical, and electron microscopic studies confirmed the diagnosis. One of the patients, a 65-year-old-woman, has no evidence of recurrence or distant metastasis 3 years after surgery and radiotherapy, whereas another patient, a 56-year-old man, died of distant metastasis 6 months after surgery and radiotherapy. Conclusions. We present two cases of malignant melanoma of the lacrimal sac that masqueraded as chronic dacryocystitis. Head and neck surgeons should be aware of this disease entity when encountered with patients with epiphora and mass in the medial canthal area.

Original languageEnglish
Pages (from-to)809-813
Number of pages5
JournalHead and Neck
Volume23
Issue number9
DOIs
Publication statusPublished - 2001 Aug 27

Fingerprint

Nasolacrimal Duct
Lacrimal Apparatus Diseases
Melanoma
Radiotherapy
Dacryocystitis
Neoplasm Metastasis
Neck
Head
Electrons
Light
Recurrence
Neoplasms

Keywords

  • HMB-45
  • Lacrimal sac
  • Malignant melanoma
  • Metastasis
  • Ultrastructural

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Two cases of primary malignant melanoma of the lacrimal sac. / Lee, Heung Man; Kang, Hee Joon; Choi, Geon; Chae, Sungwon; Kim, Chul Hwan; Hwang, Soon Jae; Lee, Sang Hag.

In: Head and Neck, Vol. 23, No. 9, 27.08.2001, p. 809-813.

Research output: Contribution to journalArticle

Lee, Heung Man ; Kang, Hee Joon ; Choi, Geon ; Chae, Sungwon ; Kim, Chul Hwan ; Hwang, Soon Jae ; Lee, Sang Hag. / Two cases of primary malignant melanoma of the lacrimal sac. In: Head and Neck. 2001 ; Vol. 23, No. 9. pp. 809-813.
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AU - Choi, Geon

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AU - Hwang, Soon Jae

AU - Lee, Sang Hag

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N2 - Background. Malignancy of the lacrimal sac is rare, and primary malignant melanoma in this region is extremely rare. Methods. We report two cases of malignant melanoma of the lacrimal sac presented with epiphora and a palpable mass in the medial canthal area. We performed radical surgery and radiation therapy. Results. The light microscopic, immunohistochemical, and electron microscopic studies confirmed the diagnosis. One of the patients, a 65-year-old-woman, has no evidence of recurrence or distant metastasis 3 years after surgery and radiotherapy, whereas another patient, a 56-year-old man, died of distant metastasis 6 months after surgery and radiotherapy. Conclusions. We present two cases of malignant melanoma of the lacrimal sac that masqueraded as chronic dacryocystitis. Head and neck surgeons should be aware of this disease entity when encountered with patients with epiphora and mass in the medial canthal area.

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