Two cases of transfusion related acute lung injury

Ju Lee Kyoung, Ok Kim Hye, Ha Kim Jung, Sil Ha Eun, Yong Jung Jin, Hyeun Lee Seung, Joong Kim Se, Kyung Ju Moon, Joo Lee Eun, Hae Kang Eun, Hwan Jung Ki, Yong Lee Sung, Yeub Lee Sang, Hyeong Kim Je, Chol Shin, Jeong Shim Jae, Ho In Kwang, Ho Kang Kyung, Hwa Yoo Se

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Transfusion related acute lung injury (TRALI) is a serious, potentially life-threatening complication of transfusion therapy that is sometimes under diagnosed and under reported. Patients with TRALI present with dyspnea/respiratory distress and fever. The symptoms, signs and chest radiological findings in TRALI are similar to transfusion associated circulatory overload, which makes it is difficult to distinguish it from circulatory overload. Although the mortality rate in cases of TRALI is relatively low, TRALI is the third most common cause of fatal transfusion reactions next to ABO blood type incompatibility and hepatitis. Mild-to-moderate cases of TRALI may be misdiagnosed as volume overload. Recently, we encountered two cases where the patients suffered from dyspnea and fever after a transfusion, and review of the relevant literature.

Original languageEnglish
Pages (from-to)473-478
Number of pages6
JournalTuberculosis and Respiratory Diseases
Volume61
Issue number5
DOIs
Publication statusPublished - 2006 Nov

Keywords

  • Acute lung injury
  • Blood transfusion
  • Pulmonary reaction
  • TRALI

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

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