Two different renal cell carcinomas and multiple angiomyolipomas in a patient with tuberous sclerosis

Sung Gu Kang, Young Hwii Ko, Seok Ho Kang, Jin Kim, Chul Hwan Kim, Hong Seok Park, Du Geon Moon, Jeong Gu Lee, Je Jong Kim, Jun Cheon

    Research output: Contribution to journalArticlepeer-review

    9 Citations (Scopus)

    Abstract

    We report a case of tuberous sclerosis associated with two histologically different renal cell carcinomas (RCCs) and multiple angiomyolipomas (AMLs) in the same kidney. A 43-year-old female was admitted to our hospital with left flank pain and a huge palpable mass in the left flank area. Abdominal computed tomography revealed two concurrent RCCs and multiple AMLs in the left kidney. Because of the clinical suspicion of RCC, the patient underwent left radical nephrectomy. On gross examination, the total size of the resected left kidney was 30.5x17x8 cm. Microscopically, the upper pole tumor features were consistent with chromophobe RCC and the midpole tumor was a clear-cell RCC. The multifocal masses in the remaining remnant parenchyma were AMLs. Six months after surgery, the patient is healthy without signs of tumor recurrence.

    Original languageEnglish
    Pages (from-to)729-732
    Number of pages4
    JournalKorean Journal of Urology
    Volume51
    Issue number10
    DOIs
    Publication statusPublished - 2010 Oct

    Keywords

    • Angiomyolipoma
    • Clear cell renal carcinoma
    • Renal cell carcinoma
    • Tuberous sclerosis

    ASJC Scopus subject areas

    • Urology

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