Two-photon fluorescent probes for acidic vesicles in live cells and tissue

Hwan Myung Kim, Myoung Jin An, Jin Hee Hong, Byeong Ha Jeong, Ohyun Kwon, Ju Yong Hyon, Seok Cheol Hong, Kyoung Jin Lee, Bong-Rae Cho

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

(Figure Presented) Move with the groove: Two-photon fluorescent pH probes and a two-photon lysotracker (AL1) can visualize acidic vesicles in live cells and living tissue for a long period of time without mistargeting and photobleaching problems. Using AL1, vesicles can be tracked in real time (see picture).

Original languageEnglish
Pages (from-to)2231-2234
Number of pages4
JournalAngewandte Chemie - International Edition
Volume47
Issue number12
DOIs
Publication statusPublished - 2008 Mar 7

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Fluorescent Dyes
Photons
Tissue
Photobleaching
Red DND-99

Keywords

  • Acidity
  • Fluorescent probes
  • Live tissue
  • Two-photon microscopy
  • Vesicles

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Medicine(all)

Cite this

Two-photon fluorescent probes for acidic vesicles in live cells and tissue. / Kim, Hwan Myung; An, Myoung Jin; Hong, Jin Hee; Jeong, Byeong Ha; Kwon, Ohyun; Hyon, Ju Yong; Hong, Seok Cheol; Lee, Kyoung Jin; Cho, Bong-Rae.

In: Angewandte Chemie - International Edition, Vol. 47, No. 12, 07.03.2008, p. 2231-2234.

Research output: Contribution to journalArticle

Kim, Hwan Myung ; An, Myoung Jin ; Hong, Jin Hee ; Jeong, Byeong Ha ; Kwon, Ohyun ; Hyon, Ju Yong ; Hong, Seok Cheol ; Lee, Kyoung Jin ; Cho, Bong-Rae. / Two-photon fluorescent probes for acidic vesicles in live cells and tissue. In: Angewandte Chemie - International Edition. 2008 ; Vol. 47, No. 12. pp. 2231-2234.
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