Two-photon fluorescent probes for metal ions

Hwan Myung Kim, Bong Rae Cho

Research output: Contribution to journalReview article

111 Citations (Scopus)

Abstract

Two-photon microscopy (TPM) has become an indispensible tool in biology and medicine owing to the capability of imaging the intact tissue for a long period of time. To make it a versatile tool in biology, a variety of two-photon probes for specific applications are needed. In this context, many research groups are developing two-photon probes for various applications. In this Focus Review, we summarize recent results on model studies and selected examples of two-photon probes that can detect intracellular free metal ions in live cells and tissues to provide a guideline for the design of useful two-photon probes for various in vivo imaging applications. In search for metals: In this Focus Review, recent model studies and selected examples are described of two-photon probes that can detect intracellular free metal ions in live cells and tissues to provide a guideline for the design of useful two-photon probes for various in vivo imaging applications.

Original languageEnglish
Pages (from-to)58-69
Number of pages12
JournalChemistry - An Asian Journal
Volume6
Issue number1
DOIs
Publication statusPublished - 2011 Jan 3

Keywords

  • fluorescent probes
  • in vivo imaging
  • metal ions
  • nonlinear spectroscopy
  • two-photon microscopy

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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