Two-photon lysotrackers for in vivo imaging

Ji Hoon Son, Chang Su Lim, Ji Hee Han, Isravel Antony Danish, Hwan Myung Kim, Bong Rae Cho

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

We report two-photon Lysotrackers (CLT-blue and CLT-yellow) that can be excited by 750-840 nm femtosecond laser pulses and emit at 470 and 550 nm, respectively. They can be easily loaded into cells and tissue slices for visualization of lysosomes in live cells and tissues for a long period of time through two-photon microscopy. When combined with appropriate two-photon probes for other biological targets, these novel probes would greatly facilitate the two-photon microscopy colocalization experiments. (Figure presented)

Original languageEnglish
Pages (from-to)8113-8116
Number of pages4
JournalJournal of Organic Chemistry
Volume76
Issue number19
DOIs
Publication statusPublished - 2011 Oct 7

ASJC Scopus subject areas

  • Organic Chemistry

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  • Cite this

    Son, J. H., Lim, C. S., Han, J. H., Danish, I. A., Kim, H. M., & Cho, B. R. (2011). Two-photon lysotrackers for in vivo imaging. Journal of Organic Chemistry, 76(19), 8113-8116. https://doi.org/10.1021/jo201504h