Type and incidence of soft tissue sarcomas in Korea: 2001-2007

Kyung Un Choi, Hae Youn Kang, Heasoo Koo, Mi Seon Kwon, Dong Hoon Kim, Mi Jung Kim, Su Jin Kim, Young Sill Kim, Chul Hwan Kim, Yong Koo Park, Hye Rim Park, Seung Sam Paik, Jin Young Yoo, Anhi Lee, Jae Hyuk Lee, Hyekyung Lee, Kyu Yun Jang, Young Chae Chu, Joon Hyuk Choi

Research output: Contribution to journalArticle

Abstract

Background: The Korean Bone and Soft Tissue Pathology Study Group of the Korean Society of Pathologists conducted a nationwide retrospective analysis of soft tissue sarcoma (STS) to provide the clinicopathologic characteristics of STS within the population of the Republic of Korea. Methods: The cases of STS were collected during a 7-year period (2001-2007) from 19 institutes in Korea. All cases were classified according to the histologic criteria proposed by the World Health Organization. Clinicopathologic data were reviewed. Results: Data from 722 patients (median age, 50 years) were collected. Data showed a slight male predominance. The most frequent types of STS in decreasing order were liposarcoma, malignant fibrous histiocytoma, leiomyosarcoma, and synovial sarcoma. STS occurred throughout the body, although approximately half (47.8%) were located in the extremities. The majority of STS was histologically classified as high grade with a large tumor size (>5 cm). The overall survival rate for the patients was 76.3% (median follow-up time, 26 months; range, 1 to 89 months). Histologic grade, tumor size, American Joint Committee on Cancer stage, tumor site, and resection status were prognostic. Significant independent adverse prognostic factors were large tumor size (>5 cm) and tumor site other than extremities. Conclusions: We reported the distribution and characteristics of STS in the Republic of Korea.

Original languageEnglish
Pages (from-to)557-563
Number of pages7
JournalKorean Journal of Pathology
Volume45
Issue number6
DOIs
Publication statusPublished - 2011 Dec 1

Keywords

  • Incidence
  • Korea
  • Prognosis
  • Sarcoma
  • Type

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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    Choi, K. U., Kang, H. Y., Koo, H., Kwon, M. S., Kim, D. H., Kim, M. J., Kim, S. J., Kim, Y. S., Kim, C. H., Park, Y. K., Park, H. R., Paik, S. S., Yoo, J. Y., Lee, A., Lee, J. H., Lee, H., Jang, K. Y., Chu, Y. C., & Choi, J. H. (2011). Type and incidence of soft tissue sarcomas in Korea: 2001-2007. Korean Journal of Pathology, 45(6), 557-563. https://doi.org/10.4132/KoreanJPathol.2011.45.6.659