Abstract
Background: The Korean Bone and Soft Tissue Pathology Study Group of the Korean Society of Pathologists conducted a nationwide retrospective analysis of soft tissue sarcoma (STS) to provide the clinicopathologic characteristics of STS within the population of the Republic of Korea. Methods: The cases of STS were collected during a 7-year period (2001-2007) from 19 institutes in Korea. All cases were classified according to the histologic criteria proposed by the World Health Organization. Clinicopathologic data were reviewed. Results: Data from 722 patients (median age, 50 years) were collected. Data showed a slight male predominance. The most frequent types of STS in decreasing order were liposarcoma, malignant fibrous histiocytoma, leiomyosarcoma, and synovial sarcoma. STS occurred throughout the body, although approximately half (47.8%) were located in the extremities. The majority of STS was histologically classified as high grade with a large tumor size (>5 cm). The overall survival rate for the patients was 76.3% (median follow-up time, 26 months; range, 1 to 89 months). Histologic grade, tumor size, American Joint Committee on Cancer stage, tumor site, and resection status were prognostic. Significant independent adverse prognostic factors were large tumor size (>5 cm) and tumor site other than extremities. Conclusions: We reported the distribution and characteristics of STS in the Republic of Korea.
Original language | English |
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Pages (from-to) | 557-563 |
Number of pages | 7 |
Journal | Korean Journal of Pathology |
Volume | 45 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2011 Dec |
Keywords
- Incidence
- Korea
- Prognosis
- Sarcoma
- Type
ASJC Scopus subject areas
- Pathology and Forensic Medicine