Ultra-sensitive direct detection of silver ions via Kelvin probe force microscopy

Jinsung Park, Sangmyung Lee, Kuewhan Jang, Sung Soo Na

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Nanotoxicity is receiving great importance due to its potential impact on human health and environment and due to rapid development in the field of nanoscale research and industry. Herein, we report the Kelvin probe force microscope (KPPM)-based nanotoxicity material detection using surface potential difference. In general, it is difficult to measure the size of ion (Ag+) using a conventional atomic force microscope (AFM) because of the limited resolution. In this study, we have demonstrated that KPFM is capable of ultra-sensitive detection of silver ion with silver specific DNA by a single droplet. Furthermore, the measured surface potentials for Ag+ and DNA binding enable the detection performance for a practical sample that is general drinking water. Remarkably, the KPFM based silver ion detection enables an insight into the coordination chemistry, which plays an important role in early detection of toxicity. This implies that KPFM based detection system opens a new avenue for water testing sensor.

Original languageEnglish
Pages (from-to)299-304
Number of pages6
JournalBiosensors and Bioelectronics
Volume60
DOIs
Publication statusPublished - 2014 Oct 15

Fingerprint

Atomic Force Microscopy
Silver
Microscopic examination
Surface potential
Ions
Microscopes
DNA
Open systems
Potable water
Drinking Water
Toxicity
Industry
Health
Water
Sensors
Testing
Research

Keywords

  • DNA-metal interaction
  • Kelvin probe force microscope
  • Silver ion
  • Single droplet
  • Surface potential

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Biotechnology
  • Electrochemistry

Cite this

Ultra-sensitive direct detection of silver ions via Kelvin probe force microscopy. / Park, Jinsung; Lee, Sangmyung; Jang, Kuewhan; Na, Sung Soo.

In: Biosensors and Bioelectronics, Vol. 60, 15.10.2014, p. 299-304.

Research output: Contribution to journalArticle

Park, Jinsung ; Lee, Sangmyung ; Jang, Kuewhan ; Na, Sung Soo. / Ultra-sensitive direct detection of silver ions via Kelvin probe force microscopy. In: Biosensors and Bioelectronics. 2014 ; Vol. 60. pp. 299-304.
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