Ultrasonographic Endometrial Features in Tubal Pregnancy: Are They Predictive Factors of Successful Medical Treatment?

Ji Eun Lim, Tak Kim, Nak Woo Lee, Min Jeong Oh, Hyun Joo Seol, Nan Hee Jung, Sung Hoon Park, So Eun Jung, Il Hae Park, Hai Joong Kim

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The aim of this study was to explain possible relationships in cases of ectopic pregnancy between sonographic endometrial features and treatment outcome following methotrexate (MTX) injection. A total of 157 cases of unruptured tubal pregnancy were diagnosed and treated systemically with MTX. The sonographic endometrial pattern, endometrial thickness and treatment outcome were retrospectively analyzed. There were four types of endometrial patterns: these were trilaminar, homogeneous, heterogeneous and pseudosac. Success rates following MTX treatment were different for each group: these were 64.7%, 78.4%, 50.0% and 46.2%, respectively (p = 0.0129). And the risk of treatment failure was increased 3.64 times (95% CI 1.56 to 8.49) in heterogeneous thick pattern and 4.24 times (95% CI 1.18 to 15.23) in pseudosac pattern. In conclusion, when tubal pregnancy was seen in a pseudogestational sac pattern or a heterogeneous pattern, the failure rate of medical treatment was increased. This can serve as a reference for considering the decision about medical treatment in women with unruptured tubal pregnancy. (E-mail: haijkim@korea.ac.kr).

Original languageEnglish
Pages (from-to)714-719
Number of pages6
JournalUltrasound in Medicine and Biology
Volume33
Issue number5
DOIs
Publication statusPublished - 2007 May 1

Fingerprint

Tubal Pregnancy
pregnancy
Methotrexate
Ectopic Pregnancy
Treatment Failure
Therapeutics
Injections
injection

Keywords

  • Endometrial pattern
  • Medical treatment
  • Transvaginal ultrasonography
  • Tubal pregnancy

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics

Cite this

Ultrasonographic Endometrial Features in Tubal Pregnancy : Are They Predictive Factors of Successful Medical Treatment? / Lim, Ji Eun; Kim, Tak; Lee, Nak Woo; Oh, Min Jeong; Seol, Hyun Joo; Jung, Nan Hee; Park, Sung Hoon; Jung, So Eun; Park, Il Hae; Kim, Hai Joong.

In: Ultrasound in Medicine and Biology, Vol. 33, No. 5, 01.05.2007, p. 714-719.

Research output: Contribution to journalArticle

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