Ultrasonography and electrophysiological study of median nerve in patients with essential tremor

Hye Lim Lee, Ji Sun Kim, Hanjun Kim, Il Soo Kim, Jae Whan Kim, Ye Eun Kim, Seong Beom Koh

Research output: Contribution to journalArticle

Abstract

Essential tremor (ET) is a common movement disorder characterized by postural or kinetic tremor. We aimed to evaluate median nerve enlargement in patients with ET using ultrasonography (USG). Thirty-eight hands from 19 patients with ET and 24 hands from 13 controls underwent nerve conduction studies (NCS) and USG at the wrist. Tremor severity was measured using the Fahn–Tolosa–Marin Tremor Rating Scale (FTM-TRS). The median nerve cross sectional area (mCSA) in USG and NCS parameters were compared using ANCOVA. We evaluated the correlation between mCSA and NCS parameters or FTM-TRS scores using linear regression analysis. mCSA was significantly larger (p<0.001) and NCS parameters were different in two groups. Also, mCSA was negatively correlated with part B and C scores of FTM-TRS (p<0.001 and p = 0.039, respectively). In conclusion, median nerve enlargement with the changes of NCS parameters was observed and correlated with the severity of tremor in patients with ET.

Original languageEnglish
Article numbere0215750
JournalPLoS ONE
Volume14
Issue number4
DOIs
Publication statusPublished - 2019 Apr 1

Fingerprint

Essential Tremor
Ultrasonography
Median Nerve
Tremor
ultrasonography
Neural Conduction
nerve tissue
rating scales
Linear regression
Regression analysis
Hand
Kinetics
Movement Disorders
Wrist
hands
Linear Models
movement disorders
Regression Analysis
regression analysis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Ultrasonography and electrophysiological study of median nerve in patients with essential tremor. / Lee, Hye Lim; Kim, Ji Sun; Kim, Hanjun; Kim, Il Soo; Kim, Jae Whan; Kim, Ye Eun; Koh, Seong Beom.

In: PLoS ONE, Vol. 14, No. 4, e0215750, 01.04.2019.

Research output: Contribution to journalArticle

Lee, Hye Lim ; Kim, Ji Sun ; Kim, Hanjun ; Kim, Il Soo ; Kim, Jae Whan ; Kim, Ye Eun ; Koh, Seong Beom. / Ultrasonography and electrophysiological study of median nerve in patients with essential tremor. In: PLoS ONE. 2019 ; Vol. 14, No. 4.
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