Unusual regiospecificity in syn elimination from trans-2-chloro-3-fluoro-2,3-dihydrobenzofuran promoted by complex base

Richard A. Bartsch, Bong-Rae Cho, Michael J. Pugia

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Abstract

Elimination from trans-2-chloro-3-fluoro-2,3-dihydrobenzofuran induced by NaNH 2-NaO-t-Bu in THF results in syn dehydrofluorination to the exclusion of β-aryl-activated syn dehydrochlorination.

Original languageEnglish
JournalJournal of Organic Chemistry
Volume52
Issue number24
Publication statusPublished - 1987 Dec 1
Externally publishedYes

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ASJC Scopus subject areas

  • Organic Chemistry

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