Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome

Mi Mi Oh; Byeong Kuk Ham; Seok Ho Kang; Jae Hyun Bae; Je Jong Kim; Ki Hwan Yoo; Duck Ki Yoon; Du Geon Moon

doi:10.1007/s00240-011-0364-z

Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome

Mi Mi Oh, Byeong Kuk Ham, Seok Ho Kang, Jae Hyun Bae, Je Jong Kim, Ki Hwan Yoo, Duck Ki Yoon, Du Geon Moon

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Lesch-Nyhan syndrome is a rare sex-linked disorder of purine metabolism that is caused by a mutation in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene which causes marked hyperuricemia and hyperuricosuria, with signs of gouty arthritis and uric acid stone disease in early childhood. We report a case of renal pelvis calculi which was dissolved within 10 days of urine alkalinization and hydration.

Original language	English
Pages (from-to)	417-419
Number of pages	3
Journal	Urological Research
Volume	39
Issue number	5
DOIs	https://doi.org/10.1007/s00240-011-0364-z
Publication status	Published - 2011 Oct

Keywords

Lesch-Nyhan syndrome
Stones
Urine alkalinization

ASJC Scopus subject areas

Urology

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10.1007/s00240-011-0364-z

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abstract = "Lesch-Nyhan syndrome is a rare sex-linked disorder of purine metabolism that is caused by a mutation in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene which causes marked hyperuricemia and hyperuricosuria, with signs of gouty arthritis and uric acid stone disease in early childhood. We report a case of renal pelvis calculi which was dissolved within 10 days of urine alkalinization and hydration.",

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author = "Oh, {Mi Mi} and Ham, {Byeong Kuk} and Kang, {Seok Ho} and Bae, {Jae Hyun} and Kim, {Je Jong} and Yoo, {Ki Hwan} and Yoon, {Duck Ki} and Moon, {Du Geon}",

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AU - Oh, Mi Mi

AU - Ham, Byeong Kuk

AU - Kang, Seok Ho

AU - Bae, Jae Hyun

AU - Kim, Je Jong

AU - Yoo, Ki Hwan

AU - Yoon, Duck Ki

AU - Moon, Du Geon

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AB - Lesch-Nyhan syndrome is a rare sex-linked disorder of purine metabolism that is caused by a mutation in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene which causes marked hyperuricemia and hyperuricosuria, with signs of gouty arthritis and uric acid stone disease in early childhood. We report a case of renal pelvis calculi which was dissolved within 10 days of urine alkalinization and hydration.

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KW - Urine alkalinization

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Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome

Abstract

Keywords

ASJC Scopus subject areas

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