Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome

Mi-Mi Oh, Byeong Kuk Ham, Seok Ho Kang, Jae Hyun Bae, Je-Jong Kim, Kee Hwan Yoo, Duck Ki Yoon, Du Geon Moon

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Lesch-Nyhan syndrome is a rare sex-linked disorder of purine metabolism that is caused by a mutation in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene which causes marked hyperuricemia and hyperuricosuria, with signs of gouty arthritis and uric acid stone disease in early childhood. We report a case of renal pelvis calculi which was dissolved within 10 days of urine alkalinization and hydration.

Original languageEnglish
Pages (from-to)417-419
Number of pages3
JournalUrological Research
Volume39
Issue number5
DOIs
Publication statusPublished - 2011 Oct 1

Fingerprint

Physiological Sexual Dysfunctions
Lesch-Nyhan Syndrome
Gouty Arthritis
Hypoxanthine Phosphoribosyltransferase
Hyperuricemia
Kidney Pelvis
Kidney Calculi
Uric Acid
Urine
Mutation
Genes
purine

Keywords

  • Lesch-Nyhan syndrome
  • Stones
  • Urine alkalinization

ASJC Scopus subject areas

  • Urology

Cite this

Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome. / Oh, Mi-Mi; Ham, Byeong Kuk; Kang, Seok Ho; Bae, Jae Hyun; Kim, Je-Jong; Yoo, Kee Hwan; Yoon, Duck Ki; Moon, Du Geon.

In: Urological Research, Vol. 39, No. 5, 01.10.2011, p. 417-419.

Research output: Contribution to journalArticle

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