Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy

Hyun Ji Lee, Chang-Hee Lee, Jeong Woo Kim, Yang Shin Park, Jongmee Lee, Kyeong Ah Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objectives To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer. Methods 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a “target” or “non-target” appearance. The relationship of appearance or SI ratio with tumor response was analyzed. Results A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8%) vs. 4/18 (22.2%)], and it was associated with a better response [p = 0.048]. Conclusion HBP analysis may be useful to predict the response to chemotherapy and survival.

Original languageEnglish
Pages (from-to)127-131
Number of pages5
JournalClinical Imaging
Volume43
DOIs
Publication statusPublished - 2017 May 1

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Breast Neoplasms
Neoplasm Metastasis
Drug Therapy
Liver
Control Groups
Survival
Neoplasms
gadolinium ethoxybenzyl DTPA

Keywords

  • Breast cancer liver metastases
  • Chemotherapy response
  • Gadoxetic acid
  • Hepatobiliary phase (HBP)
  • MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy. / Lee, Hyun Ji; Lee, Chang-Hee; Kim, Jeong Woo; Park, Yang Shin; Lee, Jongmee; Kim, Kyeong Ah.

In: Clinical Imaging, Vol. 43, 01.05.2017, p. 127-131.

Research output: Contribution to journalArticle

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abstract = "Objectives To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer. Methods 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a “target” or “non-target” appearance. The relationship of appearance or SI ratio with tumor response was analyzed. Results A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8{\%}) vs. 4/18 (22.2{\%})], and it was associated with a better response [p = 0.048]. Conclusion HBP analysis may be useful to predict the response to chemotherapy and survival.",
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AU - Park, Yang Shin

AU - Lee, Jongmee

AU - Kim, Kyeong Ah

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