Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy

Hyun Ji Lee, Chang Hee Lee, Jeong Woo Kim, Yang Shin Park, Jongmee Lee, Kyeong Ah Kim

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    Objectives To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer. Methods 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a “target” or “non-target” appearance. The relationship of appearance or SI ratio with tumor response was analyzed. Results A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8%) vs. 4/18 (22.2%)], and it was associated with a better response [p = 0.048]. Conclusion HBP analysis may be useful to predict the response to chemotherapy and survival.

    Original languageEnglish
    Pages (from-to)127-131
    Number of pages5
    JournalClinical Imaging
    Volume43
    DOIs
    Publication statusPublished - 2017 May 1

    Keywords

    • Breast cancer liver metastases
    • Chemotherapy response
    • Gadoxetic acid
    • Hepatobiliary phase (HBP)
    • MRI

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging

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