Serum-free media containing no animal-derived components were assessed for their efficacy to produce live attenuated varicella virus. Serum-free medium containing an ultrafiltrate of soy protein acid hydrolysate and lipid resulted in a viral production yield comparable to media containing fetal bovine serum, indicating that varicella virus can be produced without the risk of contamination associated with the use of bovine serum.
- plant hydrolysate
- Serum-free medium
- Virus culture
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology