Value of CT added to ultrasonography for the diagnosis of lymph node metastasis in patients with thyroid cancer

Young Hen Lee, Ji hoon Kim, Jung Hwan Baek, So Lyung Jung, Sun Won Park, Jinna Kim, Tae Jin Yun, Eun Ju Ha, Kyu Eun Lee, Soon Young Kwon, Kyung Sook Yang, Dong Gyu Na

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: The benefit of CT for the diagnosis of lymph node metastasis in patients with thyroid cancer is still unclear. Methods: Three hundred fifty-one patients with thyroid cancers from 7 hospitals were prospectively enrolled in order to compare diagnostic performance between a combination of ultrasound and CT (ultrasound/CT) and ultrasound alone for prediction of lymph node metastasis and to calculate patient-based benefits of CT added to ultrasound. Results: Of 801 pathologically proven neck levels, ultrasound/CT showed higher sensitivities in both central and lateral compartments and improved accuracy in the lateral compartment compared to ultrasound alone. In the retropharyngeal/superior mediastinal compartment, although CT could detect lymph node metastasis an ultrasound could not. Patient-based benefit was demonstrated in 13.1% of patients (46/351), and was higher in patients with cancers >1 cm than cancers ≤1 cm. Conclusion: In patients with thyroid cancer, CT improved surgical planning by enhancing the sensitivity for lymph node metastasis and by detecting lymph node metastasis that was overlooked with ultrasound alone.

Original languageEnglish
Pages (from-to)2137-2148
Number of pages12
JournalHead and Neck
Volume40
Issue number10
DOIs
Publication statusPublished - 2018 Oct 1

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Thyroid Neoplasms
Ultrasonography
Lymph Nodes
Neoplasm Metastasis
Cancer Care Facilities
Neoplasms
Neck

Keywords

  • CT
  • lymph node
  • metastasis
  • thyroid cancer
  • ultrasonography

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Value of CT added to ultrasonography for the diagnosis of lymph node metastasis in patients with thyroid cancer. / Lee, Young Hen; Kim, Ji hoon; Baek, Jung Hwan; Jung, So Lyung; Park, Sun Won; Kim, Jinna; Yun, Tae Jin; Ha, Eun Ju; Lee, Kyu Eun; Kwon, Soon Young; Yang, Kyung Sook; Na, Dong Gyu.

In: Head and Neck, Vol. 40, No. 10, 01.10.2018, p. 2137-2148.

Research output: Contribution to journalArticle

Lee, YH, Kim, JH, Baek, JH, Jung, SL, Park, SW, Kim, J, Yun, TJ, Ha, EJ, Lee, KE, Kwon, SY, Yang, KS & Na, DG 2018, 'Value of CT added to ultrasonography for the diagnosis of lymph node metastasis in patients with thyroid cancer', Head and Neck, vol. 40, no. 10, pp. 2137-2148. https://doi.org/10.1002/hed.25202
Lee, Young Hen ; Kim, Ji hoon ; Baek, Jung Hwan ; Jung, So Lyung ; Park, Sun Won ; Kim, Jinna ; Yun, Tae Jin ; Ha, Eun Ju ; Lee, Kyu Eun ; Kwon, Soon Young ; Yang, Kyung Sook ; Na, Dong Gyu. / Value of CT added to ultrasonography for the diagnosis of lymph node metastasis in patients with thyroid cancer. In: Head and Neck. 2018 ; Vol. 40, No. 10. pp. 2137-2148.
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AU - Kim, Jinna

AU - Yun, Tae Jin

AU - Ha, Eun Ju

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AU - Yang, Kyung Sook

AU - Na, Dong Gyu

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