Value of echo-Doppler derived pulmonary vascular resistance, net-atrioventricular compliance and tricuspid annular velocity in determining exercise capacity in patients with mitral stenosis

Eui Young Choi, Jaemin Shim, Sung Ai Kim, Young Shim Chi, Se Jung Yoon, Seok Min Kang, Donghoon Choi, Jong Won Ha, Se Joong Rim, Yangsoo Jang, Namsik Chung

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: The present study sought to determine if echo-Doppler-derived pulmonary vascular resistance (PVRecho), net-atrioventricular compliance (Cn) and tricuspid peak systolic annular velocity (Sa), as parameters of right ventricular function, have value in predicting exercise capacity in patients with mitral stenosis (MS). Methods and Results: Thirty-two patients with moderate or severe MS without left ventricular systolic dysfunction were studied. After comprehensive echo-Doppler measurements, including PVRecho, tricuspid Sa and left-sided Cn, supine bicycle exercise echo and concomitant respiratory gas analysis were performed. Measurements during 5 cardiac cycles representing the mean heart rate were averaged. Increment of resting PVRecho (r=-0.416, p=0.018) and decrement of resting Sa (r=0.433, p=0.013) and Cn (r=0.469, p=0.007) were significantly associated with decrease in %V̇O 2 peak. The predictive accuracy for %V̇O2 peak could increase by combining these parameters as Sa/PVRecho (r=0.500, p=0.004) or Cn·(Sa/PVRecho) (r=0.572, p=0.001) independent of mitral valve area, mean diastolic pressure gradients or presence of atrial fibrillation. Conclusions: Measurement of PVRecho, Cn and Sa might provide important information about the exercise capacity of patients with MS.

Original languageEnglish
Pages (from-to)1721-1727
Number of pages7
JournalCirculation Journal
Volume71
Issue number11
DOIs
Publication statusPublished - 2007 Dec 17
Externally publishedYes

Fingerprint

Mitral Valve Stenosis
Vascular Resistance
Compliance
Exercise
Right Ventricular Function
Left Ventricular Dysfunction
Mitral Valve
Atrial Fibrillation
Heart Rate
Gases
Blood Pressure

Keywords

  • Doppler echocardiography
  • Exercise capacity
  • Mitral stenosis
  • Pulmonary vascular resistance
  • Tricuspid annular velocity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology

Cite this

Value of echo-Doppler derived pulmonary vascular resistance, net-atrioventricular compliance and tricuspid annular velocity in determining exercise capacity in patients with mitral stenosis. / Choi, Eui Young; Shim, Jaemin; Kim, Sung Ai; Chi, Young Shim; Yoon, Se Jung; Kang, Seok Min; Choi, Donghoon; Ha, Jong Won; Rim, Se Joong; Jang, Yangsoo; Chung, Namsik.

In: Circulation Journal, Vol. 71, No. 11, 17.12.2007, p. 1721-1727.

Research output: Contribution to journalArticle

Choi, Eui Young ; Shim, Jaemin ; Kim, Sung Ai ; Chi, Young Shim ; Yoon, Se Jung ; Kang, Seok Min ; Choi, Donghoon ; Ha, Jong Won ; Rim, Se Joong ; Jang, Yangsoo ; Chung, Namsik. / Value of echo-Doppler derived pulmonary vascular resistance, net-atrioventricular compliance and tricuspid annular velocity in determining exercise capacity in patients with mitral stenosis. In: Circulation Journal. 2007 ; Vol. 71, No. 11. pp. 1721-1727.
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abstract = "Background: The present study sought to determine if echo-Doppler-derived pulmonary vascular resistance (PVRecho), net-atrioventricular compliance (Cn) and tricuspid peak systolic annular velocity (Sa), as parameters of right ventricular function, have value in predicting exercise capacity in patients with mitral stenosis (MS). Methods and Results: Thirty-two patients with moderate or severe MS without left ventricular systolic dysfunction were studied. After comprehensive echo-Doppler measurements, including PVRecho, tricuspid Sa and left-sided Cn, supine bicycle exercise echo and concomitant respiratory gas analysis were performed. Measurements during 5 cardiac cycles representing the mean heart rate were averaged. Increment of resting PVRecho (r=-0.416, p=0.018) and decrement of resting Sa (r=0.433, p=0.013) and Cn (r=0.469, p=0.007) were significantly associated with decrease in {\%}V̇O 2 peak. The predictive accuracy for {\%}V̇O2 peak could increase by combining these parameters as Sa/PVRecho (r=0.500, p=0.004) or Cn·(Sa/PVRecho) (r=0.572, p=0.001) independent of mitral valve area, mean diastolic pressure gradients or presence of atrial fibrillation. Conclusions: Measurement of PVRecho, Cn and Sa might provide important information about the exercise capacity of patients with MS.",
keywords = "Doppler echocardiography, Exercise capacity, Mitral stenosis, Pulmonary vascular resistance, Tricuspid annular velocity",
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T1 - Value of echo-Doppler derived pulmonary vascular resistance, net-atrioventricular compliance and tricuspid annular velocity in determining exercise capacity in patients with mitral stenosis

AU - Choi, Eui Young

AU - Shim, Jaemin

AU - Kim, Sung Ai

AU - Chi, Young Shim

AU - Yoon, Se Jung

AU - Kang, Seok Min

AU - Choi, Donghoon

AU - Ha, Jong Won

AU - Rim, Se Joong

AU - Jang, Yangsoo

AU - Chung, Namsik

PY - 2007/12/17

Y1 - 2007/12/17

N2 - Background: The present study sought to determine if echo-Doppler-derived pulmonary vascular resistance (PVRecho), net-atrioventricular compliance (Cn) and tricuspid peak systolic annular velocity (Sa), as parameters of right ventricular function, have value in predicting exercise capacity in patients with mitral stenosis (MS). Methods and Results: Thirty-two patients with moderate or severe MS without left ventricular systolic dysfunction were studied. After comprehensive echo-Doppler measurements, including PVRecho, tricuspid Sa and left-sided Cn, supine bicycle exercise echo and concomitant respiratory gas analysis were performed. Measurements during 5 cardiac cycles representing the mean heart rate were averaged. Increment of resting PVRecho (r=-0.416, p=0.018) and decrement of resting Sa (r=0.433, p=0.013) and Cn (r=0.469, p=0.007) were significantly associated with decrease in %V̇O 2 peak. The predictive accuracy for %V̇O2 peak could increase by combining these parameters as Sa/PVRecho (r=0.500, p=0.004) or Cn·(Sa/PVRecho) (r=0.572, p=0.001) independent of mitral valve area, mean diastolic pressure gradients or presence of atrial fibrillation. Conclusions: Measurement of PVRecho, Cn and Sa might provide important information about the exercise capacity of patients with MS.

AB - Background: The present study sought to determine if echo-Doppler-derived pulmonary vascular resistance (PVRecho), net-atrioventricular compliance (Cn) and tricuspid peak systolic annular velocity (Sa), as parameters of right ventricular function, have value in predicting exercise capacity in patients with mitral stenosis (MS). Methods and Results: Thirty-two patients with moderate or severe MS without left ventricular systolic dysfunction were studied. After comprehensive echo-Doppler measurements, including PVRecho, tricuspid Sa and left-sided Cn, supine bicycle exercise echo and concomitant respiratory gas analysis were performed. Measurements during 5 cardiac cycles representing the mean heart rate were averaged. Increment of resting PVRecho (r=-0.416, p=0.018) and decrement of resting Sa (r=0.433, p=0.013) and Cn (r=0.469, p=0.007) were significantly associated with decrease in %V̇O 2 peak. The predictive accuracy for %V̇O2 peak could increase by combining these parameters as Sa/PVRecho (r=0.500, p=0.004) or Cn·(Sa/PVRecho) (r=0.572, p=0.001) independent of mitral valve area, mean diastolic pressure gradients or presence of atrial fibrillation. Conclusions: Measurement of PVRecho, Cn and Sa might provide important information about the exercise capacity of patients with MS.

KW - Doppler echocardiography

KW - Exercise capacity

KW - Mitral stenosis

KW - Pulmonary vascular resistance

KW - Tricuspid annular velocity

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