TY - JOUR
T1 - Variation in Sleep Stability with Differences in Severity of Sleep-Disordered Breathing in Children
AU - Seo, Min Young
AU - Han, Mun Soo
AU - Jeong, Yong Jun
AU - Lee, Min Kyu
AU - Park, Seongbin
AU - Hwang, Sun Jin
AU - Lee, Seung Hoon
N1 - Funding Information:
The study was funded by the Korea University Ansan Hospital Grant. (O200321).
Publisher Copyright:
© 2020 The American Laryngological, Rhinological and Otological Society, Inc.
PY - 2021/2
Y1 - 2021/2
N2 - Objectives: The aim of this study was to analyze the association between obstructive sleep apnea (OSA) severity and various cardiopulmonary coupling (CPC) parameters in children with OSA. Study design: Retrospective cross-sectional study. Methods: A cross-sectional study was conducted among 117 children (aged 7.96 ± 3.54 years, 86 male) who underwent both full-night polysomnography (PSG) and CPC for suspicion of sleep-disordered breathing (SDB). We analyzed the association between various CPC and PSG findings. Results: The apnea-hypopnea index (AHI) was negatively correlated with high frequency coupling (HFC, r = −0.374, P <.001) and very low frequency coupling (VLFC, r = −0.192, P =.038) and positively correlated with low frequency coupling (LFC, r = 0.503, P <.001), elevated low frequency coupling (e-LFC, r = 0.475, P <.001), and narrow and broad band e-LFC (e-LFCNB and e-LFCBB; r = 0.221, P =.016 and r = 0.468, P <.001, respectively). The arousal index was negatively correlated with HFC (r = − 0.466, P <.001) and positively correlated with LFC, e-LFC, e-LFCNB, and e-LFCBB (r = 0.543, r = 0.460, r = 0.239, and r = 0.445, respectively; all P <.001). In addition, we also found a significant difference in various CPC values according to OSA severity. Conclusion: CPC parameters accurately reflect sleep fragmentation and OSA severity in children. Thus, we can verify objective sleep quality using CPC analysis, which is a simple method of analyzing sleep stability in children with SDB. Level of Evidence: 4 Laryngoscope, 131:435–439, 2021.
AB - Objectives: The aim of this study was to analyze the association between obstructive sleep apnea (OSA) severity and various cardiopulmonary coupling (CPC) parameters in children with OSA. Study design: Retrospective cross-sectional study. Methods: A cross-sectional study was conducted among 117 children (aged 7.96 ± 3.54 years, 86 male) who underwent both full-night polysomnography (PSG) and CPC for suspicion of sleep-disordered breathing (SDB). We analyzed the association between various CPC and PSG findings. Results: The apnea-hypopnea index (AHI) was negatively correlated with high frequency coupling (HFC, r = −0.374, P <.001) and very low frequency coupling (VLFC, r = −0.192, P =.038) and positively correlated with low frequency coupling (LFC, r = 0.503, P <.001), elevated low frequency coupling (e-LFC, r = 0.475, P <.001), and narrow and broad band e-LFC (e-LFCNB and e-LFCBB; r = 0.221, P =.016 and r = 0.468, P <.001, respectively). The arousal index was negatively correlated with HFC (r = − 0.466, P <.001) and positively correlated with LFC, e-LFC, e-LFCNB, and e-LFCBB (r = 0.543, r = 0.460, r = 0.239, and r = 0.445, respectively; all P <.001). In addition, we also found a significant difference in various CPC values according to OSA severity. Conclusion: CPC parameters accurately reflect sleep fragmentation and OSA severity in children. Thus, we can verify objective sleep quality using CPC analysis, which is a simple method of analyzing sleep stability in children with SDB. Level of Evidence: 4 Laryngoscope, 131:435–439, 2021.
KW - Sleep-disordered breathing
KW - cardiopulmonary coupling
KW - child
KW - polysomnography
KW - sleep stability
UR - http://www.scopus.com/inward/record.url?scp=85085610453&partnerID=8YFLogxK
U2 - 10.1002/lary.28769
DO - 10.1002/lary.28769
M3 - Article
AN - SCOPUS:85085610453
SN - 0023-852X
VL - 131
SP - 435
EP - 439
JO - Laryngoscope
JF - Laryngoscope
IS - 2
ER -