Vinyl sulfone synthesisviacopper-catalyzed three-component decarboxylative addition

Seunghwan An, Kwang Ho Song, Sunwoo Lee

Research output: Contribution to journalArticlepeer-review

Abstract

The synthesis of vinyl sulfone derivativesviathe reaction of arylpropiolic acids, K2S2O5, and aryl boronic acids is reported. The CuBr2/1,10-phenanthroline catalytic system in the presence of acetic acid provides the desired vinyl sulfones in moderate to good yield. Furthermore, the methodology features excellent functional group tolerance.

Original languageEnglish
Pages (from-to)7827-7831
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume19
Issue number36
DOIs
Publication statusPublished - 2021 Sep 28

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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