The synthesis of vinyl sulfone derivativesviathe reaction of arylpropiolic acids, K2S2O5, and aryl boronic acids is reported. The CuBr2/1,10-phenanthroline catalytic system in the presence of acetic acid provides the desired vinyl sulfones in moderate to good yield. Furthermore, the methodology features excellent functional group tolerance.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry