Abstract
Objectives To characterize voiding symptoms during the peri- and post-menopausal periods and to investigate related hormonal changes.
Methods We enrolled a total of 55 patients between February 10, 2013, and August 15, 2013, to participate in this cross-sectional study. To characterize patients' voiding symptoms, we administered voiding questionnaires, including the International Prostate Symptom Score (IPSS), Overactive Bladder Symptom Score (OABSS), and Sandvik Severity Index. Measured hormones included E2, FSH, TSH, prolactin, progesterone, and testosterone.
Results In the univariate analysis, there were significant intergroup differences for all of the hormones except progesterone. Among the voiding symptoms, straining (IPSS question 1), frequency (IPSS question 2), and SUI were significantly different between the two groups (p = 0.039. 0.010, and 0.017, respectively). In the multivariate analysis, frequency (IPSS question 2) and SUI were significantly different between the two groups (p = 0.020 and 0.011, respectively). Among the hormones, only testosterone was marginally different between the two groups (p = 0.059).
Conclusions During the transition to menopause, voiding symptoms, such as frequency, can potentially worsen in the peri-menopausal period, and SUI is more prevalent in the post-menopausal period. Additionally, testosterone may have a role in voiding changes that occur during the menopausal transition.
| Original language | English |
|---|---|
| Pages (from-to) | 311-315 |
| Number of pages | 5 |
| Journal | Maturitas |
| Volume | 79 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2014 Nov 1 |
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Keywords
- Lower urinary tract symptoms
- Menopause
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Obstetrics and Gynaecology
Cite this
Voiding characteristics and related hormonal changes in peri-menopausal and post-menopausal women : A preliminary study. / Kwon, Jong Kyu; Kim, Jae Heon; Choi, Hoon; Chang, In Ho; Park, Bo Ra; Kwon, Soon Sun; Lee, Eun Sil; Choi, Gyu Yeon; Lee, Jeong Jae; Lee, Im Soon.
In: Maturitas, Vol. 79, No. 3, 01.11.2014, p. 311-315.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Voiding characteristics and related hormonal changes in peri-menopausal and post-menopausal women
T2 - A preliminary study
AU - Kwon, Jong Kyu
AU - Kim, Jae Heon
AU - Choi, Hoon
AU - Chang, In Ho
AU - Park, Bo Ra
AU - Kwon, Soon Sun
AU - Lee, Eun Sil
AU - Choi, Gyu Yeon
AU - Lee, Jeong Jae
AU - Lee, Im Soon
PY - 2014/11/1
Y1 - 2014/11/1
N2 - Objectives To characterize voiding symptoms during the peri- and post-menopausal periods and to investigate related hormonal changes.Methods We enrolled a total of 55 patients between February 10, 2013, and August 15, 2013, to participate in this cross-sectional study. To characterize patients' voiding symptoms, we administered voiding questionnaires, including the International Prostate Symptom Score (IPSS), Overactive Bladder Symptom Score (OABSS), and Sandvik Severity Index. Measured hormones included E2, FSH, TSH, prolactin, progesterone, and testosterone.Results In the univariate analysis, there were significant intergroup differences for all of the hormones except progesterone. Among the voiding symptoms, straining (IPSS question 1), frequency (IPSS question 2), and SUI were significantly different between the two groups (p = 0.039. 0.010, and 0.017, respectively). In the multivariate analysis, frequency (IPSS question 2) and SUI were significantly different between the two groups (p = 0.020 and 0.011, respectively). Among the hormones, only testosterone was marginally different between the two groups (p = 0.059).Conclusions During the transition to menopause, voiding symptoms, such as frequency, can potentially worsen in the peri-menopausal period, and SUI is more prevalent in the post-menopausal period. Additionally, testosterone may have a role in voiding changes that occur during the menopausal transition.
AB - Objectives To characterize voiding symptoms during the peri- and post-menopausal periods and to investigate related hormonal changes.Methods We enrolled a total of 55 patients between February 10, 2013, and August 15, 2013, to participate in this cross-sectional study. To characterize patients' voiding symptoms, we administered voiding questionnaires, including the International Prostate Symptom Score (IPSS), Overactive Bladder Symptom Score (OABSS), and Sandvik Severity Index. Measured hormones included E2, FSH, TSH, prolactin, progesterone, and testosterone.Results In the univariate analysis, there were significant intergroup differences for all of the hormones except progesterone. Among the voiding symptoms, straining (IPSS question 1), frequency (IPSS question 2), and SUI were significantly different between the two groups (p = 0.039. 0.010, and 0.017, respectively). In the multivariate analysis, frequency (IPSS question 2) and SUI were significantly different between the two groups (p = 0.020 and 0.011, respectively). Among the hormones, only testosterone was marginally different between the two groups (p = 0.059).Conclusions During the transition to menopause, voiding symptoms, such as frequency, can potentially worsen in the peri-menopausal period, and SUI is more prevalent in the post-menopausal period. Additionally, testosterone may have a role in voiding changes that occur during the menopausal transition.
KW - Lower urinary tract symptoms
KW - Menopause
UR - http://www.scopus.com/inward/record.url?scp=84908545425&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84908545425&partnerID=8YFLogxK
U2 - 10.1016/j.maturitas.2014.07.011
DO - 10.1016/j.maturitas.2014.07.011
M3 - Article
C2 - 25150899
AN - SCOPUS:84908545425
VL - 79
SP - 311
EP - 315
JO - Maturitas
JF - Maturitas
SN - 0378-5122
IS - 3
ER -