Warfarin-induced leukocytoclastic vasculitis

Hwan Kim Jae; Yeong Jeong Se; Hong Seo Soo; Wook Son Sang; Hwan Kim Il

Warfarin-induced leukocytoclastic vasculitis

Hwan Kim Jae, Yeong Jeong Se, Hong Seo Soo, Wook Son Sang, Hwan Kim Il

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Leukocytoclastic vasculitis is a small vessel inflammatory disease, mediated mostly by deposition of immune complexes. Medications cause 10-24% of cases of leukocytoclastic vasculitic skin lesions, but warfarin has rarely been implicated. We report a case of warfarin-induced leukocytoclastic vasculitis in a 72-year-old woman which developed 45 days after warfarin medication. Palpable purpura, hemorrhagic vesicles, and ulcers developed on both lower legs. A skin biopsy showed characteristic features of leukocytoclastic vasculitis. Warfarin was replaced by Clopidogrel, and the skin lesions gradually disappeared after 3 weeks.

Original language	English
Pages (from-to)	715-717
Number of pages	3
Journal	Korean Journal of Dermatology
Volume	46
Issue number	5
Publication status	Published - 2008 May

Keywords

Leukocytoclastic vasculitis
Warfarin

ASJC Scopus subject areas

Dermatology

Cite this

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title = "Warfarin-induced leukocytoclastic vasculitis",

abstract = "Leukocytoclastic vasculitis is a small vessel inflammatory disease, mediated mostly by deposition of immune complexes. Medications cause 10-24% of cases of leukocytoclastic vasculitic skin lesions, but warfarin has rarely been implicated. We report a case of warfarin-induced leukocytoclastic vasculitis in a 72-year-old woman which developed 45 days after warfarin medication. Palpable purpura, hemorrhagic vesicles, and ulcers developed on both lower legs. A skin biopsy showed characteristic features of leukocytoclastic vasculitis. Warfarin was replaced by Clopidogrel, and the skin lesions gradually disappeared after 3 weeks.",

keywords = "Leukocytoclastic vasculitis, Warfarin",

author = "Jae, {Hwan Kim} and Se, {Yeong Jeong} and Soo, {Hong Seo} and Sang, {Wook Son} and Il, {Hwan Kim}",

year = "2008",

month = may,

language = "English",

volume = "46",

pages = "715--717",

journal = "Korean Journal of Dermatology",

issn = "0494-4739",

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T1 - Warfarin-induced leukocytoclastic vasculitis

AU - Jae, Hwan Kim

AU - Se, Yeong Jeong

AU - Soo, Hong Seo

AU - Sang, Wook Son

AU - Il, Hwan Kim

PY - 2008/5

Y1 - 2008/5

N2 - Leukocytoclastic vasculitis is a small vessel inflammatory disease, mediated mostly by deposition of immune complexes. Medications cause 10-24% of cases of leukocytoclastic vasculitic skin lesions, but warfarin has rarely been implicated. We report a case of warfarin-induced leukocytoclastic vasculitis in a 72-year-old woman which developed 45 days after warfarin medication. Palpable purpura, hemorrhagic vesicles, and ulcers developed on both lower legs. A skin biopsy showed characteristic features of leukocytoclastic vasculitis. Warfarin was replaced by Clopidogrel, and the skin lesions gradually disappeared after 3 weeks.

AB - Leukocytoclastic vasculitis is a small vessel inflammatory disease, mediated mostly by deposition of immune complexes. Medications cause 10-24% of cases of leukocytoclastic vasculitic skin lesions, but warfarin has rarely been implicated. We report a case of warfarin-induced leukocytoclastic vasculitis in a 72-year-old woman which developed 45 days after warfarin medication. Palpable purpura, hemorrhagic vesicles, and ulcers developed on both lower legs. A skin biopsy showed characteristic features of leukocytoclastic vasculitis. Warfarin was replaced by Clopidogrel, and the skin lesions gradually disappeared after 3 weeks.

KW - Leukocytoclastic vasculitis

KW - Warfarin

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M3 - Article

AN - SCOPUS:50249188295

SN - 0494-4739

VL - 46

SP - 715

EP - 717

JO - Korean Journal of Dermatology

JF - Korean Journal of Dermatology

IS - 5

ER -

Warfarin-induced leukocytoclastic vasculitis

Abstract

Keywords

ASJC Scopus subject areas

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