Wide-spectrum Antimicrobial Packaging Materials Incorporating Nisin and Chitosan in the Coating

Ho Chan Lee, Duck Soon An, Hyun Jin Park, Dong Sun Lee

Research output: Contribution to journalArticlepeer-review

87 Citations (Scopus)


Nisin and/or chitosan were coated, in 3% concentrations, onto paper with a binder medium of vinyl acetate-ethylene co-polymer to provide antimicrobial activity for use in food packaging. The combined use of nisin and chitosan in the coating was an attempt to give a wide antimicrobial spectrum that could inhibit the growth of several food spoilage and poisonous microorganisms. The migration of the preservative from the coatings to water was evaluated at 10°C and related to the suppressed microbial growth in the water and microbial medium. After 8 days, 8.1-8.3% of nisin and 1.0-1.2% of chitosan had migrated, and the migration of each was not affected by the presence of the other. The paper coated with nisin was more effective than the chitosan-coated paper in inhibiting the Gram-positive bacterium, Listeria monocytogenes, whereas the latter was more effective against Escherichia coli O157:H7. Combined inclusion of nisin and chitosan in the coating gave antimicrobial activity against both bacterial strains, and could improve the microbial stability of milk and orange juice stored at 10°C.

Original languageEnglish
Pages (from-to)99-106
Number of pages8
JournalPackaging Technology and Science
Issue number3
Publication statusPublished - 2003 May


  • Acetic acid
  • Binder
  • Escherichia coli O157:H7
  • Listeria monocytogenes
  • Migration

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Mechanical Engineering


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