The aim of this study was to investigate the appetite suppression effects of yeast hydrolysate (YH). Male ICR mice (8 weeks old) were randomly divided into three groups (n=6) as follows: Saline group, which was treated with saline (control); YH0.5 group, which was treated with YH 0.5 g/kg BW; and YH1 group, which was treated with YH 1 g/kg BW. At the beginning of the experiment, the mice were intraperitoneally (IP) injected with either saline or YH. The results showed that YH caused a significant attenuation of food intake in fasted mice (p<0.05) and significantly lowered serum ghrelin levels (YH0.5, 2002.22 pg/mL; YH1, 2337.65 pg/mL vs. Saline, 3363.61 pg/mL, p<0.05). This study indicates that the appetite suppression effects of YH is likely explained by the attenuation of ghrelin.
|Number of pages||3|
|Journal||Progress in Nutrition|
|Publication status||Published - 2015 Nov 30|
- Yeast hydrolysate
ASJC Scopus subject areas
- Food Science
- Nutrition and Dietetics