Yeast hydrolysate as a functional anti-obesity ingredient: Appetite suppressive effects of yeast hydrolysate in food-deprived mice

Ki Bae Hong, Eun Young Jung, Jae Hwan Kim, Un Jae Chang, Hyung Joo Suh

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The aim of this study was to investigate the appetite suppression effects of yeast hydrolysate (YH). Male ICR mice (8 weeks old) were randomly divided into three groups (n=6) as follows: Saline group, which was treated with saline (control); YH0.5 group, which was treated with YH 0.5 g/kg BW; and YH1 group, which was treated with YH 1 g/kg BW. At the beginning of the experiment, the mice were intraperitoneally (IP) injected with either saline or YH. The results showed that YH caused a significant attenuation of food intake in fasted mice (p<0.05) and significantly lowered serum ghrelin levels (YH0.5, 2002.22 pg/mL; YH1, 2337.65 pg/mL vs. Saline, 3363.61 pg/mL, p<0.05). This study indicates that the appetite suppression effects of YH is likely explained by the attenuation of ghrelin.

Original languageEnglish
Pages (from-to)262-264
Number of pages3
JournalProgress in Nutrition
Volume17
Issue number3
Publication statusPublished - 2015 Nov 30

Keywords

  • Appetite
  • Ghrelin
  • Obesity
  • Yeast hydrolysate

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

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