Yeast hydrolysate reduces body fat of dietary obese rats

K. M. Kim, U. J. Chang, D. H. Kang, J. M. Kim, Y. M. Choi, Hyung Joo Suh

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Abstract

The purpose of this study was to assess the antiobesity effect of the yeast hydrolysate (DNF) on the body weight, body fat and plasma lipids levels of high-fat fed rats. The weight gain of the HF (high fat diet) (162.58 ± 6.68 g) was significantly (p < 0.05) greater than that of DNF-1, DNF-2, (high fat diet with DNF of 0.5 and 1.0 g/kg body weight, respectively) and control groups (143.19 ± 7.33 g, 139.20 ± 8.36 g, 130.23 ± 8.02 g, respectively). The wet weight of the epididymal fat and the perirenal fat pads of the DNF-1, DNF-2 and control groups were reduced significantly (p < 0.05). A significant (p < 0.05) increase of HDL-cholesterol level of the DNF-2 and control groups was observed. However, there was no significant difference between DNF-1 and DNF-2. It was also found that the triacylglycerol (TG) levels decreased significantly (p < 0.05) in the DNF-2 group from that of the HF, but there was no significant (p < 0.05) difference between DNF-1 and DNF-2.

Original languageEnglish
Pages (from-to)950-953
Number of pages4
JournalPhytotherapy Research
Volume18
Issue number11
DOIs
Publication statusPublished - 2004 Nov 1

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Keywords

  • Hypolipidaemic effect
  • Triacyglycerol
  • Yeast hydrolysate

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

Kim, K. M., Chang, U. J., Kang, D. H., Kim, J. M., Choi, Y. M., & Suh, H. J. (2004). Yeast hydrolysate reduces body fat of dietary obese rats. Phytotherapy Research, 18(11), 950-953. https://doi.org/10.1002/ptr.1582